Genetically modified microorganisms and genetically modified organisms are those which are not dangerous for humans and animals, but which could alter animals, plants, microbiological substances and ecosystems in such a way as cannot occur naturally. 

Genetically modified microorganisms and genetically modified organisms are not subject to the requirements of ADN when authorized for use by the competent authorities of the countries of origin, transit and destination *).

Live vertebrate or invertebrate animals shall not be used to carry these substances classified under this UN number unless the substance can be carried in no other way. 

For the carriage of easily perishable substances under this UN number appropriate information shall be given, e.g.: "Cool at +2 °/+4 °C" or "Carry in frozen state" or "Do not freeze".

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*) See in particular Part C of Directive 2001/18/EC of the European Parliament and of the Council on the deliberate release into the environment of genetically modified organisms and repealing Council Directive 90/220/EEC (Official Journal of the European Communities, No. L 106, of 17 April 2001, pp. 8-14), which sets out the authorization procedures for the European Community.